منابع مشابه
Iron regulation by hepatocytes and free radicals
Iron is an essential metallic microelement for life. However, iron overload is toxic. The liver serves an important role as a storehouse for iron in the body. About 20-25 mg of iron is required each day for hemoglobin synthesis. To maintain iron homeostasis, transferrin and transferrin receptors are primarily involved in the uptake of iron into hepatocytes, ferritin in its storage, and ferropor...
متن کاملIron, free radicals, and oxidative injury.
Iron metabolism and superoxide metabolism are clearly interactive, especially under pathological conditions. Each can exacerbate the toxicity of the other. Iron overload may amplify the damaging effects of superoxide overproduction in a very broad spectrum of inflammatory or ischemia-related conditions. Furthermore, chronic oxidative stress may modulate iron uptake and storage, leading to a sel...
متن کاملIron , zinc , copper and
Objective. To describe the micronutrient nutritional status of a national sample of 1-11 year old Mexican children surveyed in 2006 in National Health and Nutrition Survey (ENSANUT 2006) and their association with dietary and sociodemographic factors. Materials and methods. Serum samples were used (n=5 060) to measure the concentrations of ferritin, transferrin receptor, zinc, copper and magnes...
متن کاملIron, copper and immunocompetence.
Microminerals including copper and iron are essential to immunity and health in human beings. The development of powerful tools in analytical cell biology and molecular genetics has facilitated efforts to identify specific cellular and molecular functions of trace elements in the maturation, activation and functions of host defence mechanisms. Selected recent reports about the role of copper an...
متن کاملFree Radicals and Gastric Cancer
Mahmoud Lotfy1 and Yousery E. Sherif2 1Associate Professor of Molecular Cell Biology & Immunology, Molecular and Cellular Biology Department, Genetic Engineering and Biotechnology Research Institute, Minufiya University, Sadat City, Minufiya, Egypt and Department of Applied Medical Sciences, Jouf University, Qurayat, 2Clinical Pharmacology Department, Faculty of Medicine, Mansoura University, M...
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ژورنال
عنوان ژورنال: Rheumatology
سال: 1985
ISSN: 1462-0324,1462-0332
DOI: 10.1093/rheumatology/24.2.123